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HOUDA BENRAHMA

Position: Génétique et Biologie Moléculaire

Sous-spécialités

Génétique moléculaire, cytogénétique , Bio-informatique , Biostatistique

Domaines de compétences

*Analyse des prédispositions génétiques aux maladies multifactorielles : Diabète type 2, syndrome métabolique , Hypertension ..
*Diagnostic moléculaire des maladies Génétiques : surdités héréditaires , Infertilité masculine, Glioblastomes …
* Diagnostic moléculaire des infectieuse: Covid-19
*Mise en place et équipement de plateformes de Biologie Moléculaire.

Affiliation

Faculté de Médecine

Date Parcours
Depuis Décembre 2020 Professeur Habilité en Génétique et Biologie Moléculaire. Faculté de Médecine, Université Mohammed VI des sciences de la santé, Casablanca.
Juin 2016- Décembre 2020 Professeur-Assistant en Génétique et Biologie Moléculaire, Faculté de Médecine, Université Mohammed VI des sciences de la santé, Casablanca
Mai 2014 – mai 2016 Support scientifique en Biologie Moléculaire à à Génome Biotechnologies
Décembre 2012 – Mai 2014 Stage Postdoctoral: projet international « MEDGENE » pour l’étude du diabète de type 2 et syndrome métabolique chez la population marocaine.au Laboratoire de Génétique et Biologie Moléculaire à l’Institut Pasteur du Maroc, Casablanca.
2012 Doctorat en Biologie Spécialité : Biologie Moléculaire et Génétique Humaine. Faculté des Sciences Ain Chock, Université Hassan II Ain Chock, Casablanca.
2008 Diplôme des Etudes Supérieures Approfondies (DESA).Spécialité : Biotechnologie appliquée à l’industrie et à l’environnement.Faculté des Sciences Ain Chock, Université Hassan II Ain Chock, Casablanca.
2006 Licence en Biologie. Spécialité : Biologie Générale. Faculté des Sciences Ain Chock, Université Hassan II Ain Chock, Casablanca.
2004 Diplôme des Etudes Universitaires Générales (DEUG). Spécialité : Biologie- Géologie. Faculté des Sciences Ain Chock, Université Hassan II Ain Chock, Casablanca.

Publications Article dans une revue indexée

Type de publication Intitulé Lien
Review A Review on Current Diagnostic Techniques for COVID-19 https://pubmed.ncbi.nlm.nih.gov/33593219/
Article Large scale genomic analysis of 3067 SARS-CoV-2 genomes reveals a clonal geo-distribution and a rich genetic variations of hotspots mutations. https://pubmed.ncbi.nlm.nih.gov/33170902/
Article Genomic Diversity and Hotspot Mutations in 30,983 SARS-CoV-2 Genomes: Moving Toward a Universal Vaccine for the « Confined Virus »? https://pubmed.ncbi.nlm.nih.gov/33050463/
Article Association of c.56C > G (rs3135506) Apolipoprotein A5 Gene Polymorphism with Coronary Artery Disease in Moroccan Subjects: A Case-Control Study and an Updated Meta-Analysis https://pubmed.ncbi.nlm.nih.gov/32832146/
Article Genome Sequences of Six SARS-CoV-2 Strains Isolated in Morocco, Obtained Using Oxford Nanopore MinION Technology https://pubmed.ncbi.nlm.nih.gov/32763945/
Article Diagnosis of Coronavirus Disease 2019 (COVID-19): A laboratory based study of Casablanca Morocco. https://www.publichealthinafrica.org/index.php/jphia/article/view/1458
preprint Do the Moroccan SARS-CoV-2 genetic diversity hamper the use of the developed universal vaccines in Morocco? doi: https://doi.org/10.1101/2020.06.30.181123
preprint Epidemiological description and analysis of RdRp, E and N genes dynamic by RT-PCR of SARS-CoV-2 in Moroccan population: Experience of the National Reference Laboratory (LNR)-UM6SS https://doi.org/10.1101/2020.06.18.20/135137.
preprint Time to RNA negative conversion in Moroccan COVID-19 patients: A single-center experience. DOI: 10.20944/preprints202006.0334.v1
Article Cytogenetic and FISH analysis of 93 multiple myeloma Moroccan patients. https://pubmed.ncbi.nlm.nih.gov/32573970/
Article Association analysis of genetic variants with metabolic syndrome components in the Moroccan population. https://pubmed.ncbi.nlm.nih.gov/28919193/
Article Novel variants of mitochondrial DNA associated with Type 2 diabetes mellitus in Moroccan population. https://pubmed.ncbi.nlm.nih.gov/27728995/
Article Association analysis of APOA5 rs662799 and rs3135506 polymorphisms with obesity in Moroccan patients. https://pubmed.ncbi.nlm.nih.gov/26524954/
Article Mediterranean Founder Mutation Database (MFMD): Taking Advantage from Founder Mutations in Genetics Diagnosis, Genetic Diversity and Migration History of the Mediterranean Population. https://pubmed.ncbi.nlm.nih.gov/26173767/
Article Haplotype analysis of the Apolipoprotein A5 gene in Moroccan patients with the metabolic syndrome. https://pubmed.ncbi.nlm.nih.gov/25909077/
Article Evidence for association of the E23K variant of KCNJ11 gene with type 2 diabetes in Tunisian population: population-based study and meta-analysis. https://pubmed.ncbi.nlm.nih.gov/25165692/
Article TNF A -308G>A polymorphism in Moroccan patients with type 2 diabetes mellitus: a case-control study and meta-analysis. https://pubmed.ncbi.nlm.nih.gov/24952604/
Article Association analysis of IGF2BP2, KCNJ11, and CDKAL1 polymorphisms with type 2 diabetes mellitus in a Moroccan population: a case-control study and meta-analysis. https://pubmed.ncbi.nlm.nih.gov/24898818/
Article Association of APOA5 rs662799 and rs3135506 polymorphisms with arterial hypertension in Moroccan patients. https://pubmed.ncbi.nlm.nih.gov/24684850/
Article Contribution of CDKAL1 rs7756992 and IGF2BP2 rs4402960 polymorphisms in type 2 diabetes, diabetic complications, obesity risk and hypertension in the Tunisian population. https://pubmed.ncbi.nlm.nih.gov/24636221/
Article Genetic and molecular analysis of the CLDN14 gene in Moroccan family with non-syndromic hearing loss. https://pubmed.ncbi.nlm.nih.gov/24339547/
Article Clinicopathological features and molecular analysis of primary glioblastomas in Moroccan patients. https://pubmed.ncbi.nlm.nih.gov/22865003/
Article Association of the MTHFR A1298C variant with unexplained severe male infertility. https://pubmed.ncbi.nlm.nih.gov/22457816/
Article Vitamin D Receptor Gene Polymorphisms and vitamin D status and susceptibility to Type 2 Diabetes Mellitus in Moroccans population. http://www.ijsrp.org/research-paper-0814/ijsrp-p3221.pdf
Article Relationship between Vitamin D Receptor (VDR) Gene Polymorphisms and susceptibility to Type 2 Diabetes Mellitus in Moroccans population. http://www.ijias.issr-journals.org/abstract.php?article=IJIAS-14-214-01
Article Association between polymorphism in APOC3, and Metabolic Syndrome in the Moroccan Population. http://www.ijsrp.org/research-paper-1014.php?rp=P343231
Article Association of the C677T polymorphism in the human methylenetetrahydrofolate reductase (MTHFR) gene with the genetic predisposition for type 2 diabetes mellitus in a Moroccan population. https://pubmed.ncbi.nlm.nih.gov/22103601/
Article Maternal effect and familial aggregation in a type 2 diabetic Moroccan population. https://pubmed.ncbi.nlm.nih.gov/21442339/
Article Prevalence of the mitochondrial A 1555G mutation in Moroccan patients with non-syndromic hearing loss. https://pubmed.ncbi.nlm.nih.gov/20637512/
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